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Why Choose OvoSkill

The Ultimate Treatment to Restore & Revitalize Your Fertility

Adipose-derived stem cell treatment is regarded as the new successful therapy for the treatment of  your fertility problems due to many advantages:

Rapidity

Only 20 cc of fat are required; they are collected during a quick and painless outpatient procedure.

Safety

Mesenchymal stem cell therapy is a tolerable and safe treatment for premature ovarian failure.

Simplicity

Mesenchymal stem cells are easy to isolate and expand.

No immunogenicity

Adipose-derived stem cells are minimally immunogenic, and the use of autologous stem cells mitigate any immunogenic concern.

Efficacy

Mesenchymal stem cell treatment improves hormone production, ovarian size, endometrial thickness, and endometrial blood flow.

Cryopreservation

Mesenchymal stem cells not immediately utilized can be frozen and cryopreserved for future treatment.

Stem cell treatment restores ovarian function and leads to the production of immature oocytes. In women, ultrasounds demonstrated that mesenchymal stem cell treatment improved both ovarian size and endometrial thickness of patient with premature ovarian failure. Moreover, blood flow analysis demonstrated a richer signal in the endometrium.

About Ovarian Failure

Overview

Premature ovarian failure (POF, also called primary ovarian insufficiency or early menopause) is a common gynecological endocrine disease characterized by the loss of ovarian function in women below 40 years. Most often, it is a non-reversible pathology leading to infertility.

Normally, ovaries produce hormones and eggs until the early fifties, when they stop working and most women enter menopause. However, phenomena such as the dysfunction and the depletion of follicles (the cellular aggregates in the ovaries secreting hormones that influence the menstrual cycle) lead to POF, whose prevalence is 1/250 in women under 35 years and 1/100 in women under 40 years; the consequent loss of ovarian reserve (the number of follicles remaining in a woman’s ovaries) increases the risk of infertility, severely affecting women both physically and mentally.

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Normally, ovaries produce hormones and eggs until the early fifties, when they stop working and most women enter menopause. However, phenomena such as the dysfunction and the depletion of follicles (the cellular aggregates in the ovaries secreting hormones that influence the menstrual cycle) lead to POF, whose prevalence is 1/250 in women under 35 years and 1/100 in women under 40 years; the consequent loss of ovarian reserve (the number of follicles remaining in a woman’s ovaries) increases the risk of infertility, severely affecting women both physically and mentally.

More information

Symptoms

Symptoms of premature ovarian failure are highly variable, including both manifestations of hormone deficiencies and of potential underlying disorders causing the condition.

Diagnosis can be complicated by the fact that women with this condition retain some ovarian function that can lead to fluctuation in hormone levels and possibly sporadic spontaneous ovulation.

Among ovary-related signs and symptoms are absence of menstruation (amenorrhea), infertility, estrogen deficiency, reduced ovarian follicles and elevated gonadotropins (the hormones acting on the ovaries) before the age of 40 years.

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Complications

Infertility is not the only possible consequence of POF. In fact, the premature deprivation of ovarian sex hormones that characterizes this condition leads to a number of complications affecting different systems.

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Causes

Despite ongoing efforts, premature ovarian failure causes have not yet been fully elucidated, and this condition is still a complex, heterogeneous and not fully characterized entity. In more than 90% of cases no etiology is defined, and POF is called “idiopathic”, that is “with no apparent known cause”.

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Stem cell-based Therapy

The new natural treatment for premature ovarian failure

OvoSkill is delivered through intra-ovarian injection of autologous Adipose-Derived mesenchymal Stem Cells (ADSCs), a type of stem cells capable of self-renewal and of differentiating into multiple cell types.

Our Numbers

Our Centers of Genomics and Regenerative Medicine are based in Europe (Rome, Milan and San Marino) and Middle East (Dubai). We offer the most advanced personalized expanded adipose-derived stem cell therapies and Next Generation Sequencing genomic tests for solid cancer risk management. The premium service in Regenerative Medicine include cryopreservation and expansion of stem cells for personalized anti-aging treatments, aesthetic plastic surgery, hair regeneration and wound care.

specialists (e.g. gynecologists) who rely on our services
years of expertise in Genomics and Regenerative Medicine
our stem cell factories located in the World
scientific papers on personalized autologous cell therapies

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We offer the most advanced personalized expanded adipose-derived stem cell therapies